发明授权
- 专利标题： TrkA kinase inhibitors, compositions and methods thereof
- 专利标题（中）： TrkA激酶抑制剂，组合物及其方法
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申请号： US14401941申请日： 2013-05-17
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公开(公告)号： US09181261B2公开(公告)日： 2015-11-10
- 发明人: Shawn J. Stachel , Melissa Egbertson , Edward Brnardic , Kristen G. Jones , John M. Sanders , Darrell Henze
- 申请人： Merck Sharp & Dohme Corp.
- 申请人地址： US NJ Rahway
- 专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人： Merck Sharp & Dohme Corp.
- 当前专利权人地址： US NJ Rahway
- 代理商 Sylvia A. Ayler; John C. Todaro
- 国际申请： PCT/US2013/041492 WO 20130517
- 国际公布： WO2013/176970 WO 20131128
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; C07D417/10 ; C07D471/04 ; C07D277/28 ; C07D277/66 ; C07D239/34 ; C07D239/42 ; C07D277/30 ; C07D403/04 ; C07D417/12
摘要：
The present invention is directed to benzyl urea compounds, which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C.
公开/授权文献
- US20150141428A1 TrkA Kinase Inhibitors, Compositions and Methods Thereof 公开/授权日：2015-05-21
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