发明授权
- 专利标题： Drug-eluting catheter and method of manufacturing the same
- 专利标题（中）： 药物洗脱导管及其制造方法
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申请号： US12921443申请日： 2009-03-12
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公开(公告)号： US09186439B2公开(公告)日： 2015-11-17
- 发明人: Ryuichi Morishita , Hironori Nakagami , Takashi Miyake , Makoto Mitamura , Hiroaki Nakajima , Hiroaki Matsuda , Nao Suizu , Yoshihumi Kawano , Kunihiko Takagi , Hiroyuki Tsujimoto , Yusuke Tsukada , Kaori Hara , Yohei Bando
- 申请人： Ryuichi Morishita , Hironori Nakagami , Takashi Miyake , Makoto Mitamura , Hiroaki Nakajima , Hiroaki Matsuda , Nao Suizu , Yoshihumi Kawano , Kunihiko Takagi , Hiroyuki Tsujimoto , Yusuke Tsukada , Kaori Hara , Yohei Bando
- 申请人地址： JP Osaka JP Tokyo JP Osaka
- 专利权人： AnGes MG, Inc.,Medikit Co., Ltd.,Hosokawa Micron Corporation
- 当前专利权人： AnGes MG, Inc.,Medikit Co., Ltd.,Hosokawa Micron Corporation
- 当前专利权人地址： JP Osaka JP Tokyo JP Osaka
- 代理机构： Fish & Richardson P.C.
- 优先权： JP2008-063143 20080312; JP2008-249611 20080929
- 国际申请： PCT/JP2009/054720 WO 20090312
- 国际公布： WO2009/113605 WO 20090917
- 主分类号： A61L29/16
- IPC分类号： A61L29/16 ; A61M25/10 ; B05D5/00 ; A61L29/08 ; A61M25/00
摘要：
Biocompatible nanoparticles 1 which entrap a bioactive substance and whose surface is positive-charge-modified are electrically adhered to a balloon portion 9 of a catheter main body 5 through a negatively charged resin layer 11, and thus a nanoparticle layer 12 is formed. After the catheter main body 5 is indwell in vivo, the nanoparticles 1 are gradually eluted from the nanoparticle layer 12 and are effectively delivered to cells.
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