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发明授权
US09193719B2 1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities 有权
1,2,4-三唑-5-酮和具有抗癌和抗增殖活性的类似物

1,2,4-triazol-5-ones and analogs exhibiting anti-cancer and anti-proliferative activities
摘要：
Described are compounds of Formula I which find utility in the treatment of cancer, autoimmune diseases and metabolic bone disorders through inhibition of c-FMS (CSF-1R), c-KIT, and/or PDGFR kinases. These compounds also find utility in the treatment of other mammalian diseases mediated by c-FMS, c-KIT, or PDGFR kinases.
摘要（中）：

描述了通过抑制c-FMS（CSF-1R），c-KIT和/或PDGFR激酶在治疗癌症，自身免疫疾病和代谢性骨骼疾病中有用的式I化合物。 这些化合物也可用于治疗由c-FMS，c-KIT或PDGFR激酶介导的其它哺乳动物疾病。

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