发明授权
- 专利标题： Dihydroxy aromatic heterocyclic compound
- 专利标题（中）： 二羟基芳香杂环化合物
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申请号： US14358162申请日： 2012-11-14
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公开(公告)号： US09212147B2公开(公告)日： 2015-12-15
- 发明人: Takeshi Hondo , Keita Nakanishi , Tatsuya Niimi , Masaichi Warizaya , Ichiji Namatame , Katsuya Harada
- 申请人： TAKEDA PHARMACEUTICAL COMPANY LIMITED
- 申请人地址： JP Osaka
- 专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人： Takeda Pharmaceutical Company Limited
- 当前专利权人地址： JP Osaka
- 代理机构： Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- 优先权： JP2011-250143 20111115
- 国际申请： PCT/JP2012/079521 WO 20121114
- 国际公布： WO2013/073577 WO 20130523
- 主分类号： C07D401/06
- IPC分类号： C07D401/06 ; A61K31/44 ; C07D237/16 ; C07D403/12 ; C07D401/14 ; C07D405/14 ; A61K31/4412 ; A61K31/4418 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/4439 ; A61K31/444 ; A61K31/496 ; A61K31/50 ; A61K31/501 ; A61K31/5377 ; A61K31/551 ; C07D401/12 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D417/14 ; C07D471/04 ; C07D471/10 ; C07D487/04 ; C07D213/69 ; C07D403/06 ; C07D405/06 ; C07D409/06 ; C07D413/06 ; C07D413/10 ; C07D417/06 ; C07D253/07 ; C07D491/056
摘要：
Provided is a compound having a D-amino acid oxidase (DAAO) inhibitory action, and useful as for example, a prophylaxis and/or therapeutic agent for schizophrenia or neuropathic pain. The present inventors have studied a compound that inhibits DAAO, and confirm that a dihydroxy aromatic heterocyclic compound has a DAAO inhibitory action, and completed the present invention. That is, the dihydroxy aromatic heterocyclic compound of the present invention has a good DAAO inhibitory action, and can be used as a prophylaxis and/or therapeutic agent for, for example, schizophrenia or neuropathic pain.
公开/授权文献
- US20140336165A1 DIHYDROXY AROMATIC HETEROCYCLIC COMPOUND 公开/授权日：2014-11-13
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