A device and system for load driving. The device includes: an electric energy supplying unit including at least two units with output voltage adjustable; a sampling unit, with the input thereof connected to either end of a load unit for sampling the current of that end and sending the sampled current to an output voltage controller; the output voltage controller, with the input thereof connected to the output of the sampling unit for outputting voltage control signal to each unit with output voltage adjustable, according to the sampled current, so as to control the difference between the output voltage of each unit with output voltage adjustable and the maximum load voltage in a load branch to be not greater than a preset difference threshold, with the difference threshold being greater than or equal to zero. The device and system for load driving can improve the reliability of the driving device and can reduce the complexity of the circuit.