发明授权
US09216159B2 Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages 有权
增加烯丙胺药物化合物用于局部治疗皮肤和皮肤附属物的真菌感染的有效性

Increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of the skin and skin appendages
摘要:
The invention is an increased effectiveness of allylamine drug compounds for topical treatment of fungal infections of skin and skin appendages. The allylamine active ingredient is prepared in an acidic environment; the acidic environment altering the physiochemical properties of the active ingredient resulting in the active ingredient having a positive charge. The positive charge and enhancers used in the formula allow for increased penetration of the active ingredient through skin and skin appendages. The positively charged active ingredients are either dissolved in the vehicle directly or dissolved in a plurality of beads suspended in the vehicle. The bead structure minimizes the molecular diffusion of the positively charged active ingredient and a catalytic species through the bead structure, thus stabilizes the positively charged active ingredient inside the bead by impeding the interaction of the positively charged active ingredient and the catalytic species, and thereby extending the shelf life of the positively charged active ingredient.
信息查询
0/0