Invention Grant
- Patent Title: Process for preparing bicyclic amine derivatives
- Patent Title (中): 制备双环胺衍生物的方法
-
Application No.: US13933961Application Date: 2013-07-02
-
Publication No.: US09227901B2Publication Date: 2016-01-05
- Inventor: Yi-Yin Ku , Steven Hannick , Ashok K. Gupta
- Applicant: AbbVie Inc.
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: C07C233/23
- IPC: C07C233/23 ; C07C49/755 ; C07C49/697 ; C07C233/59 ; C07C233/60 ; C07C231/12 ; C07D207/24 ; C07C231/14 ; C07C233/14 ; C07D207/38 ; C07C233/06
Abstract:
The present invention provides a process for preparing a bicyclic amine derivative of the formula (Ia) or (Ib), comprising the rhodium-catalyzed asymmetric hydrogenation of an enamine of the formula (II), in the presence of a chiral ligand, wherein the chiral ligand is a chiral phosphine ligand.
Public/Granted literature
- US20140012015A1 PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES Public/Granted day:2014-01-09
Information query
