Invention Grant
US09228015B2 Nogo receptor antagonists and methods of increasing neurite outgrowth
有权
Nogo受体拮抗剂和增加神经突生长的方法
- Patent Title: Nogo receptor antagonists and methods of increasing neurite outgrowth
- Patent Title (中): Nogo受体拮抗剂和增加神经突生长的方法
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Application No.: US14146345Application Date: 2014-01-02
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Publication No.: US09228015B2Publication Date: 2016-01-05
- Inventor: Daniel H. S. Lee , Dingyi Wen , R. Blake Pepinsky , Jane K. Relton , Xinzhong Wang , Alexey Lugovskoy , Werner Meier , Ellen A. Garber , Laura Silvian , Paul H. Weinreb
- Applicant: Biogen Idec MA Inc.
- Applicant Address: US MA Cambridge
- Assignee: Biogen Idec MA Inc.
- Current Assignee: Biogen Idec MA Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell, JD; Nishat A. Shaikh, JD
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A01K67/027 ; C07K14/705 ; C12N15/113 ; C12N15/85 ; A61K38/17 ; A61K39/395 ; A61K48/00 ; A61K39/00
Abstract:
Disclosed are immunogenic Nogo receptor-1 polypeptides, Nogo receptor-1 antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof and nucleic acids encoding the same. Also disclosed are Nogo receptor antagonist polynucleotides. Also disclosed are compositions comprising, and methods for making and using, such Nogo receptor antibodies, antigen-binding fragments thereof, soluble Nogo receptors and fusion proteins thereof, nucleic acids encoding the same and antagonist polynucleotides.
Public/Granted literature
- US20140227266A1 NOGO Receptor Antagonists Public/Granted day:2014-08-14
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