Signals propagating from an aggressor communication channel can cause detrimental interference in a victim communication channel. One or more noise cancellers can generate an interference compensation signal to suppress or cancel the interference based on one or more settings. A controller can execute algorithms to find preferred settings for the noise canceller(s). The controller can use a feedback signal (e.g., receive signal quality indicator) received from a victim receiver during the execution of the algorithm(s) to find the preferred settings. One exemplary algorithm includes sequentially evaluating the feedback resulting from a predetermined list of settings. Another algorithm includes determining whether to move from one setting to the next based on the feedback values for both settings. Yet another algorithm includes evaluating a number of sample settings to determine which of the sample settings result in a better feedback value and searching around that sample setting for a preferred setting.