- 专利标题: Method for searching for malodor control agent, malodor control agent, and malodor control method
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申请号: US13819882申请日: 2011-09-01
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公开(公告)号: US09233082B2公开(公告)日: 2016-01-12
- 发明人: Aya Kato , Naoko Saito , Etsuji Wakisaka
- 申请人: Aya Kato , Naoko Saito , Etsuji Wakisaka
- 申请人地址: JP Tokyo
- 专利权人: Kao Corporation
- 当前专利权人: Kao Corporation
- 当前专利权人地址: JP Tokyo
- 代理机构: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 优先权: JP2010-197759 20100903; JP2010-197825 20100903
- 国际申请: PCT/JP2011/069939 WO 20110901
- 国际公布: WO2012/029922 WO 20120308
- 主分类号: A61K31/11
- IPC分类号: A61K31/11 ; C12Q1/66 ; G01N33/50 ; G01N33/566 ; G01N33/74
摘要:
Provided are a method for searching for a malodor inhibitor by using the response of an olfactory receptor as an indicator; a method for inhibiting malodor based on the antagonism of olfactory receptors; and a malodor inhibitor. Disclosed are a method for searching for a malodor inhibitor, the method including: adding a test substance and a malodor-causing substance to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1, measuring the response of the olfactory receptor to the malodor-causing substance, identifying the test substance that suppresses the response of the olfactory receptor on the basis of the measured response, and selecting the identified test substance as a malodor inhibitor; an antagonist to any one olfactory receptor selected from the group consisting of OR51E1, OR2W1, OR10A6, OR51I2, and OR51L1; a method for inhibiting malodor using the antagonist.
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