发明授权
- 专利标题： Small molecule RNase inhibitors and methods of use
- 专利标题（中）： 小分子RNA酶抑制剂及其使用方法
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申请号： US13981015申请日： 2012-01-26
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公开(公告)号： US09233095B2公开(公告)日： 2016-01-12
- 发明人: Paul M. Dunman , Patrick D. Olson , Wayne Childers
- 申请人： Paul M. Dunman , Patrick D. Olson , Wayne Childers
- 申请人地址： US NY Rochester US NE Lincoln US PA Philadelphia
- 专利权人： University of Rochester,Board of Regents of the University of Nebraska,Temple University—Of the Commonwealth System of Higher Education
- 当前专利权人： University of Rochester,Board of Regents of the University of Nebraska,Temple University—Of the Commonwealth System of Higher Education
- 当前专利权人地址： US NY Rochester US NE Lincoln US PA Philadelphia
- 代理机构： Kilpatrick Townsend & Stockton, LLP
- 国际申请： PCT/US2012/022662 WO 20120126
- 国际公布： WO2012/103295 WO 20120802
- 主分类号： A61K31/402
- IPC分类号： A61K31/402 ; C07D207/337 ; A61K31/341 ; C07D307/68 ; C07D307/56 ; C07D405/06 ; C07D417/06 ; A61K31/427 ; A61K45/06
摘要：
Small molecule inhibitors of bacterial ribonuclease (e.g., RnpA) and methods for their synthesis and use are described herein. The methods of using the compounds include treating and preventing microbial infections and inhibiting bacterial ribonuclease. Also described herein are methods of identifying compounds for treating or preventing a microbial infection.
公开/授权文献
- US20130303585A1 SMALL MOLECULE RNASE INHIBITORS AND METHODS OF USE 公开/授权日：2013-11-14
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