Invention Grant
- Patent Title: Benzimidazolone derivatives as bromodomain inhibitors
- Patent Title (中): 苯并咪唑酮衍生物作为溴结构域抑制剂
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Application No.: US14227736Application Date: 2014-03-27
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Publication No.: US09255089B2Publication Date: 2016-02-09
- Inventor: Evangelos Aktoudianakis , Gregory Chin , Britton Kenneth Corkey , Jinfa Du , Kristyna Elbel , Robert H. Jiang , Tetsuya Kobayashi , Ruben Martinez , Samuel E. Metobo , Michael R. Mish , Sophie Shevick , David Sperandio , Hai Yang , Jeff Zablocki
- Applicant: Gilead Sciences, Inc.
- Applicant Address: US CA Foster City
- Assignee: Gilead Sciences, Inc.
- Current Assignee: Gilead Sciences, Inc.
- Current Assignee Address: US CA Foster City
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D413/04 ; C07D417/14

Abstract:
This application relates to chemical compounds which may act as inhibitors of, or which may otherwise modulate the activity of, a bromodomain-containing protein, including bromodomain-containing protein 4 (BRD4), and to compositions and formulations containing such compounds, and methods of using and making such compounds. Compounds include compounds of Formula (I) wherein R1a, R1b, R2a, R2b, R3, and X are described herein.
Public/Granted literature
- US20140296246A1 BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS Public/Granted day:2014-10-02
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