Invention Grant
- Patent Title: Oxazine derivatives and their use in the treatment of disease
-
Application No.: US14350938Application Date: 2012-10-11
-
Publication No.: US09284284B2Publication Date: 2016-03-15
- Inventor: Konstanze Hurth , Sebastien Jacquier , Rainer Machauer , Heinrich Rueeger , Marina Tintelnot-Blomley , Siem Jacob Veenstra , Markus Voegtle
- Applicant: Konstanze Hurth , Sebastien Jacquier , Rainer Machauer , Heinrich Rueeger , Marina Tintelnot-Blomley , Siem Jacob Veenstra , Markus Voegtle
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- Agent Joshua Roth
- International Application: PCT/IB2012/055521 WO 20121011
- International Announcement: WO2013/054291 WO 20130418
- Main IPC: C07D265/30
- IPC: C07D265/30 ; C07D413/04 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D471/04 ; C07D487/04 ; A61K31/5375 ; A61K31/5377
Abstract:
The invention relates to novel oxazine derivatives of formula (I), and pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of Alzheimer's Disease or diabetes via inhibition of BACE-1 or BACE-2.
Public/Granted literature
- US20140256715A1 Novel Oxazine Derivatives and their use in the Treatment of Disease Public/Granted day:2014-09-11
Information query
