发明授权
- 专利标题: System for electroporation therapy
- 专利标题(中): 电穿孔治疗系统
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申请号: US12874788申请日: 2010-09-02
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公开(公告)号: US09289606B2公开(公告)日: 2016-03-22
- 发明人: Saurav Paul , Troy T. Tegg , Israel A. Byrd , Riki Thao , Harry A. Puryear , Linda Nemec , John M. Berns
- 申请人: Saurav Paul , Troy T. Tegg , Israel A. Byrd , Riki Thao , Harry A. Puryear , Linda Nemec , John M. Berns
- 申请人地址: US MN St. Paul
- 专利权人: St. Jude Medical, Atrial Fibrillation Division, Inc.
- 当前专利权人: St. Jude Medical, Atrial Fibrillation Division, Inc.
- 当前专利权人地址: US MN St. Paul
- 代理机构: Dykema Gossett PLLC
- 主分类号: A61B18/18
- IPC分类号: A61B18/18 ; A61N1/32 ; A61B18/14 ; A61B18/00
摘要:
Catheter systems include direction-sensitive, multi-polar tip electrode assemblies for electroporation-mediated therapy, electroporation-induced primary necrosis therapy and electric field-induced apoptosis therapy, including configurations for producing narrow, linear lesions as well as distributed, wide area lesions. A monitoring system for electroporation therapy includes a mechanism for delivering electrochromic dyes to a tissue site as well as a fiber optic arrangement to optically monitor the progress of the therapy as well as to confirm success post-therapy. A fiber optic temperature sensing electrode catheter includes a tip electrode having a cavity whose inner surface is impregnated or coated with thermochromic/thermotropic material that changes color with changes in temperature. An optic fiber/detector arrangement monitors the thermochromic or thermotropic materials, acquiring a light signal and generating an output signal indicative of the spectrum of the light signal. An analyzer determines an electrode temperature based on the detector output and predetermined spectrum versus temperature calibration data.
公开/授权文献
- US20120059255A1 CATHETER SYSTEMS 公开/授权日:2012-03-08