Invention Grant
US09290473B2 Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO)
有权
磷脂酰肌醇-3-激酶（PI3）和一氧化氮（NO）诱导剂的抑制剂
- Patent Title: Inhibitors of phosphatidylinositol-3-kinase (PI3) and inducers of nitric oxide (NO)
- Patent Title (中): 磷脂酰肌醇-3-激酶（PI3）和一氧化氮（NO）诱导剂的抑制剂
-
Application No.: US13144263Application Date: 2010-01-12
-
Publication No.: US09290473B2Publication Date: 2016-03-22
- Inventor: Santu Bandyopadhyay , Bikas Chandra Pal , Jaisankar Parasuraman , Siddhartha Roy , Jayashree Bagchi Chakrabotry , Indrani Choudhury Mukherjee , Sanjit Kumar Mahato , Aditya Konar , Srabanti Rakshit , Labanya Mandal , Dipyaman Ganguly , Kausik Paul , Anirban Manna , Jayaraman Vinayagam , Churala Pal
- Applicant: Santu Bandyopadhyay , Bikas Chandra Pal , Jaisankar Parasuraman , Siddhartha Roy , Jayashree Bagchi Chakrabotry , Indrani Choudhury Mukherjee , Sanjit Kumar Mahato , Aditya Konar , Srabanti Rakshit , Labanya Mandal , Dipyaman Ganguly , Kausik Paul , Anirban Manna , Jayaraman Vinayagam , Churala Pal
- Applicant Address: IN New Delhi
- Assignee: COUCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Current Assignee: COUCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Current Assignee Address: IN New Delhi
- Agency: Cooper & Dunham LLP
- Agent John P. White
- Priority: IN44/DEL/2009 20090112
- International Application: PCT/IB2010/000040 WO 20100112
- International Announcement: WO2010/079423 WO 20100715
- Main IPC: A61K31/36
- IPC: A61K31/36 ; C07C215/54 ; C07C255/33 ; C07C39/10 ; C07D317/06 ; C07C251/40 ; C07C251/66 ; C07C255/36 ; C07C255/38
Abstract:
The present invention relates to compounds of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula 1 for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.
Public/Granted literature
- US20120190738A1 INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO) Public/Granted day:2012-07-26
Information query
