Invention Grant
US09309282B2 Solid phase for mixed-mode chromatographic purification of proteins
有权
用于蛋白质混合模式色谱纯化的固相
- Patent Title: Solid phase for mixed-mode chromatographic purification of proteins
- Patent Title (中): 用于蛋白质混合模式色谱纯化的固相
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Application No.: US13654574Application Date: 2012-10-18
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Publication No.: US09309282B2Publication Date: 2016-04-12
- Inventor: Jiali Liao , Lee Olech , Hong Chen , Xuemei He , Russell Frost
- Applicant: Bio-Rad Laboratories, Inc.
- Applicant Address: US CA Hercules
- Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee Address: US CA Hercules
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07K1/16 ; C07K16/06 ; B01D15/08
Abstract:
Proteins are purified by a mixed-mode chromatography system formed by attaching a ligand with cation exchange and hydrophobic functionalities to a large-pore support matrix, the only linkage between the ligand and the support matrix being a chain having a backbone of no more than three atoms between the hydrophobic group and the support matrix.
Public/Granted literature
- US20130102761A1 SOLID PHASE FOR MIXED-MODE CHROMATOGRAPHIC PURIFICATION OF PROTEINS Public/Granted day:2013-04-25
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