发明授权
- 专利标题： Pyridine derivatives as agonists of the CB2 receptor
- 专利标题（中）： 吡啶衍生物作为CB2受体的激动剂
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申请号： US13486057申请日： 2012-06-01
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公开(公告)号： US09321727B2公开(公告)日： 2016-04-26
- 发明人: Caterina Bissantz , Uwe Grether , Paul Hebeisen , Atsushi Kimbara , Qingping Liu , Matthias Nettekoven , Marco Prunotto , Stephan Roever , Mark Rogers-Evans , Tanja Schulz-Gasch , Christoph Ullmer , Zhiwei Wang , Wulun Yang
- 申请人： Caterina Bissantz , Uwe Grether , Paul Hebeisen , Atsushi Kimbara , Qingping Liu , Matthias Nettekoven , Marco Prunotto , Stephan Roever , Mark Rogers-Evans , Tanja Schulz-Gasch , Christoph Ullmer , Zhiwei Wang , Wulun Yang
- 申请人地址： US NJ Nutley
- 专利权人： Hoffmann-La Roche Inc.
- 当前专利权人： Hoffmann-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 优先权： WOPCT/CN2011/075606 20110610
- 主分类号： C07D211/68
- IPC分类号： C07D211/68 ; C07D211/80 ; C07D213/02 ; C07D401/00 ; C07D419/00 ; C07D417/00 ; C07D405/00 ; C07D213/62 ; C07D213/78 ; C07D211/78 ; C07D211/90 ; C07D213/81 ; C07D401/04 ; C07D401/14 ; C07D405/04 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D413/12 ; C07D413/14 ; C07D417/06 ; C07D417/12 ; C07D491/107
摘要：
The invention relates to a compound of formula (I) Wherein R1, R2, R3 and R4 are defined as in the description and in the claims. The said compounds of the invention are preferential agoniste of the Carsonabinocid Receptor 2 and thus useful as medicaments and may be used in treatment of chronic pain, atherosclerosis, ischemic/reperfusion injury and other related diseases.A representative compound of this invention is 6-cyclopropylmethoxy-5-(tetrahydro-pyradine-2-carboxglic acid [1-methyl-1-(5-methyl-(1,2,4]oxadiazol-3-yl)-ethyl)-amide.
公开/授权文献
- US09290451B2 Pyridine derivatives as agonists of the CB2 receptor 公开/授权日：2016-03-22
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