Invention Grant
- Patent Title: Mutants of L-asparaginase
- Patent Title (中): L-天冬酰胺酶的突变体
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Application No.: US13819702Application Date: 2011-09-01
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Publication No.: US09322008B2Publication Date: 2016-04-26
- Inventor: Bishwajit Kundu , Saurabh Bansal , Prashant Mishra
- Applicant: Bishwajit Kundu , Saurabh Bansal , Prashant Mishra
- Applicant Address: IN New Delhi IN New Delhi
- Assignee: Indian Institute of Technology,Department of Biotechnology, Ministry of Science and Technology
- Current Assignee: Indian Institute of Technology,Department of Biotechnology, Ministry of Science and Technology
- Current Assignee Address: IN New Delhi IN New Delhi
- Agency: Morrison & Foerster LLP
- Priority: IN2090/DEL/2010 20100901
- International Application: PCT/IB2011/002018 WO 20110901
- International Announcement: WO2012/028945 WO 20120308
- Main IPC: C12N9/82
- IPC: C12N9/82 ; A61K38/46 ; A23L1/015
Abstract:
The present invention relates to a mutant of L-asparaginase enzyme characterized in having high thermostability, pH stability and no glutaminase activity useful for therapeutics and the process of preparing the same. The present invention specifically relates to mutants MTCC 5580, MTCC 5581 and MTCC 5582 characterized in having higher stability, no glutaminase activity etc., to allow their usage in the form of improved protein therapeutics.
Public/Granted literature
- US20130330316A1 MUTANTS OF L-ASPARAGINASE Public/Granted day:2013-12-12
Information query
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