The present invention relates to a method for compensating a power amplification unit of a wireless RF module that includes a baseband unit, a RF transceiver unit, a power amplification unit and a control unit. The baseband unit is connected to the power amplification unit through the control unit and the RF transceiver unit. Based on the characteristic of the power amplification unit, the baseband unit provides a control signal to regulate the output signal characteristic of the power amplification unit, or provides a RF transceiver unit control signal to regulate the characteristics of the RF signal being transmitted by the RF transceiver unit to the power amplification unit, or to regulate the characteristics of the baseband signal being transmitted to the RF transceiver unit, enabling the characteristics of the output signal of the power amplification unit to meet the specifications of the related system.