发明授权
- 专利标题： Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors
- 专利标题（中）： 取代苯基 - 脾脏酪氨酸激酶（Syk）抑制剂
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申请号： US14422419申请日： 2013-08-15
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公开(公告)号： US09353066B2公开(公告)日： 2016-05-31
- 发明人: Andrew M. Haidle , Jason Burch , Daniel Guay , Jacques Yves Gauthier , Joel Robichaud , Jean Francois Fournier , John Michael Ellis , Matthew Christopher , Solomon D. Kattar , Graham F. Smith , Alan B. Northrup
- 申请人： Merck Sharp & Dohme Corp. , Merck Canada Inc.
- 申请人地址： US NJ Rahway CA Kirkland, Quebec
- 专利权人： Merck Sharp & Dohme Corp.,Merck Canada Inc.
- 当前专利权人： Merck Sharp & Dohme Corp.,Merck Canada Inc.
- 当前专利权人地址： US NJ Rahway CA Kirkland, Quebec
- 代理商 Eric A. Meade; Anna L. Cocuzzo
- 国际申请： PCT/US2013/055133 WO 20130815
- 国际公布： WO2014/031438 WO 20140227
- 主分类号： C07D239/42
- IPC分类号： C07D239/42 ; C07D403/12 ; A61K31/506 ; A61K31/505 ; C07D401/12 ; C07D239/47
摘要：
The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
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