Invention Grant
- Patent Title: Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors
- Patent Title (中): 取代苯基 - 脾脏酪氨酸激酶（Syk）抑制剂
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Application No.: US14422419Application Date: 2013-08-15
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Publication No.: US09353066B2Publication Date: 2016-05-31
- Inventor: Andrew M. Haidle , Jason Burch , Daniel Guay , Jacques Yves Gauthier , Joel Robichaud , Jean Francois Fournier , John Michael Ellis , Matthew Christopher , Solomon D. Kattar , Graham F. Smith , Alan B. Northrup
- Applicant: Merck Sharp & Dohme Corp. , Merck Canada Inc.
- Applicant Address: US NJ Rahway CA Kirkland, Quebec
- Assignee: Merck Sharp & Dohme Corp.,Merck Canada Inc.
- Current Assignee: Merck Sharp & Dohme Corp.,Merck Canada Inc.
- Current Assignee Address: US NJ Rahway CA Kirkland, Quebec
- Agent Eric A. Meade; Anna L. Cocuzzo
- International Application: PCT/US2013/055133 WO 20130815
- International Announcement: WO2014/031438 WO 20140227
- Main IPC: C07D239/42
- IPC: C07D239/42 ; C07D403/12 ; A61K31/506 ; A61K31/505 ; C07D401/12 ; C07D239/47
Abstract:
The invention provides certain substituted phenyl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, Rcy, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).
Public/Granted literature
- US20150232428A1 SUBSTITUTED PHENYL-SPLEEN TYROSINE KINASE (SYK) INHIBITORS Public/Granted day:2015-08-20
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