Invention Grant
- Patent Title: Substituted aromatic oligomers
- Patent Title (中): 取代的芳族低聚物
-
Application No.: US14232442Application Date: 2012-07-13
-
Publication No.: US09359311B2Publication Date: 2016-06-07
- Inventor: Peter Åsberg , Kristin Hammer , Johan Olsson , Martin Henriksson
- Applicant: Peter Åsberg , Kristin Hammer , Johan Olsson , Martin Henriksson
- Applicant Address: AT St. Radegund/Graz
- Assignee: NEUROSCIOS GMBH
- Current Assignee: NEUROSCIOS GMBH
- Current Assignee Address: AT St. Radegund/Graz
- Agency: Foley & Lardner LLP
- Priority: SE1150682 20110714
- International Application: PCT/SE2012/050837 WO 20120713
- International Announcement: WO2013/009259 WO 20130117
- Main IPC: C07D261/20
- IPC: C07D261/20 ; C07D235/20 ; C07D333/18 ; C07D409/10 ; C07D333/60 ; C07D409/14 ; C07D409/04 ; C07D333/24 ; C07D413/10 ; C07D417/14 ; C07D413/14 ; C07D403/10

Abstract:
The present invention relates to novel chemical compounds formula (I) (C)n—B-(A)m-B—(C)n (I) wherein m is 0 or 1, and n is independently 0, 1, 2 or 3, A, each B and each C are independently selected from phenylene and five- and six-membered heteroaromatic rings, and for a terminal ring B or C also from bicyclic heteroaromatic fused rings having seven to ten ring members, wherein the bond between at least two of the rings A to C may be replaced by a carbonyl group (—CO—), wherein at least two of the rings A to C are substituted with one or two groups R, and wherein each ring A to C further optionally is substituted with one or two groups R1. The compounds are useful in therapy, especially therapy of a mammal suffering from a disease involving misfolded or aggregated forms of proteins.
Public/Granted literature
- US20140135322A1 NOVEL COMPOUNDS AND THEIR USE IN THERAPY Public/Granted day:2014-05-15
Information query