Invention Grant
US09364832B2 Nanofluidic channels with gradual depth change for reducing entropic barrier of biopolymers
有权
具有逐渐深度变化的纳米流体通道，用于减少生物聚合物的熵屏障
- Patent Title: Nanofluidic channels with gradual depth change for reducing entropic barrier of biopolymers
- Patent Title (中): 具有逐渐深度变化的纳米流体通道，用于减少生物聚合物的熵屏障
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Application No.: US13944552Application Date: 2013-07-17
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Publication No.: US09364832B2Publication Date: 2016-06-14
- Inventor: Qinghuang Lin , Gustavo A. Stolovitzky , Chao Wang , Deqiang Wang
- Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
- Applicant Address: US NY Armonk
- Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
- Current Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
- Current Assignee Address: US NY Armonk
- Agency: Tutunjian & Bitetto, P.C.
- Agent Vazken Alexanian
- Main IPC: G01N27/447
- IPC: G01N27/447 ; B01L3/00 ; G01N33/487
Abstract:
A device for passing a biopolymer molecule includes a nanochannel formed between a surface relief structure, a patterned layer forming sidewalls of the nanochannel and a sealing layer formed over the patterned layer to encapsulate the nanochannel. The surface relief structure includes a three-dimensionally rounded surface that reduces a channel dimension of the nanochannel at a portion of nanochannel and gradually increases the dimension along the nanochannel toward an opening position, which is configured to receive a biopolymer.
Public/Granted literature
- US20150021187A1 NANOFLUIDIC CHANNELS WITH GRADUAL DEPTH CHANGE FOR REDUCING ENTROPIC BARRIER OF BIOPOLYMERS Public/Granted day:2015-01-22
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