- 专利标题: Fused heterocyclic compounds as ion channel modulators
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申请号: US14274422申请日: 2014-05-09
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公开(公告)号: US09371329B2公开(公告)日: 2016-06-21
- 发明人: Britton Corkey , Elfatih Elzein , Robert Jiang , Rao Kalla , Tetsuya Kobayashi , Dmitry Koltun , Xiaofen Li , Gregory Notte , Eric Parkhill , Thao Perry , Jeff Zablocki
- 申请人: Britton Corkey , Elfatih Elzein , Robert Jiang , Rao Kalla , Tetsuya Kobayashi , Dmitry Koltun , Xiaofen Li , Gregory Notte , Eric Parkhill , Thao Perry , Jeff Zablocki
- 申请人地址: US CA Foster City
- 专利权人: Gilead Sciences, Inc.
- 当前专利权人: Gilead Sciences, Inc.
- 当前专利权人地址: US CA Foster City
- 代理商 Francis O. Ginah
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; C07D471/04
摘要:
The present invention relates to compounds that are sodium channel inhibitors and to their use in the treatment of various disease states, including cardiovascular diseases and diabetes. In particular embodiments, the structure of the compounds is given by Formula I: wherein W1, W2, W3, R1, Q, X1, X2 and X3 are as described herein, to methods for the preparation and use of the compounds and to pharmaceutical compositions containing the same.
公开/授权文献
- US20140303158A1 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS 公开/授权日:2014-10-09
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