- 专利标题: Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
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申请号: US14004058申请日: 2012-02-28
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公开(公告)号: US09376467B2公开(公告)日: 2016-06-28
- 发明人: Yusuke Kono , Shuji Fujita , Hideaki Suzuki , Mari Okumoto , Takashi Nakae , Kazuhiro Chiba
- 申请人: Yusuke Kono , Shuji Fujita , Hideaki Suzuki , Mari Okumoto , Takashi Nakae , Kazuhiro Chiba
- 申请人地址: JP Tokyo
- 专利权人: JITSUBO CO., LTD.
- 当前专利权人: JITSUBO CO., LTD.
- 当前专利权人地址: JP Tokyo
- 代理机构: Andrews Kurth, LLP
- 代理商 Michael Ye
- 优先权: JP2011-052107 20110309
- 国际申请: PCT/JP2012/054895 WO 20120228
- 国际公布: WO2012/121057 WO 20120913
- 主分类号: C07K7/08
- IPC分类号: C07K7/08 ; A61K47/48 ; C07K1/00 ; C07K1/113 ; C07K7/06 ; C07K14/00
摘要:
The purpose of the present invention is to provide a cross-linked peptide containing a novel non-peptide cross-linked structure, and a method for synthesizing the same. A cross-linked peptide having a novel non-peptide cross-linked structure, a useful intermediate for synthesizing the cross-linked peptide, and a method for synthesizing the novel cross-linked peptide and the intermediate are provided. The cross-linked peptide is characterized by having an —NR— bond in the cross-linked structure. By using the method for synthesizing the cross-linked peptide, a cross-link can be freely designed and an change can be freely made to a cross-link.
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