An output over-voltage protection circuit for power factor correction, which includes a chip external compensation network, a chip external resistor divider network, a static over-voltage detection circuit, a dynamic over-voltage detection circuit and a compare circuit; The chip external compensation network is connected between the chip external resistor divider network and the dynamic over-voltage detection circuit, the chip external compensation network converts the dynamic over-voltage signal conversion to the dynamic current signal and conveys it to the dynamic over-voltage detection circuit, the dynamic over-voltage detection circuit detects the dynamic current signal and ultimately produces the dynamic over-voltage signal (DYOVP); The dynamic over-voltage signal (DYOVP) is inputted into the compare circuit, which converts the dynamic over-voltage signal (DYOVP) into a voltage compared with a reference voltage and outputs a over-voltage control signal (OVP), so as to achieve a dynamic over-voltage protection function.