Invention Grant
US09382257B2 Substituted pyrrolo[2,3-b]pyrazines as serine/threonine kinase inhibitors
有权
取代的吡咯并[2,3-b]吡嗪作为丝氨酸/苏氨酸激酶抑制剂
- Patent Title: Substituted pyrrolo[2,3-b]pyrazines as serine/threonine kinase inhibitors
- Patent Title (中): 取代的吡咯并[2,3-b]吡嗪作为丝氨酸/苏氨酸激酶抑制剂
-
Application No.: US14688724Application Date: 2015-04-16
-
Publication No.: US09382257B2Publication Date: 2016-07-05
- Inventor: Daniel Burdick , Huifen Chen , Shumei Wang , Weiru Wang
- Applicant: Genentech, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Main IPC: A61K31/4985
- IPC: A61K31/4985 ; C07D231/10 ; C07D241/38 ; C07D487/04 ; A61K45/06
![Substituted pyrrolo[2,3-b]pyrazines as serine/threonine kinase inhibitors](/abs-image/US/2016/07/05/US09382257B2/abs.jpg.150x150.jpg)
Abstract:
Compounds having the formula I wherein R1 and R2 are as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.
Public/Granted literature
- US20150218176A1 SERINE/THREONINE KINASE INHIBITORS Public/Granted day:2015-08-06
Information query
IPC分类: