The present disclosure describes methods, systems, and computer program products for three-dimensional (3D) volume rendering. One computer-implemented method includes receiving a rendering request for a volume rendering of data of a volume dataset, calling one or more database-layer rendering procedures to perform the rendering request, for each rendering procedure: retrieving data volume metadata consistent with the rendering request and retrieving data volume data consistent with rendering request, generating, by a computer and using the data volume metadata and data volume data, an image intensity buffer containing intensity and illumination data for image generation, and generating an image from the data contained in the image intensity buffer.