发明授权
- 专利标题： Derivatives of docosahexaenoylethanolamide and uses thereof
- 专利标题（中）： 二十二碳六烯酰乙醇酰胺的衍生物及其用途
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申请号： US14387410申请日： 2013-03-15
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公开(公告)号： US09422308B2公开(公告)日： 2016-08-23
- 发明人: Hee-Yong Kim , Juan Jose Marugan , Erika E. Englund , Samarjit Patnaik
- 申请人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Leydig, Voit & Mayer, Ltd.
- 国际申请： PCT/US2013/032333 WO 20130315
- 国际公布： WO2013/158302 WO 20131024
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; C07D213/40 ; C07D319/20 ; C07D205/04 ; C07C235/28 ; C07D309/04 ; C07D333/20 ; C07D235/14 ; C07C233/09 ; C07C233/13 ; C07C233/20 ; C07C233/23 ; C07C233/31 ; C07C233/38 ; C07C233/49 ; C07C255/29 ; C07D295/13 ; C07D295/135 ; C07D295/185 ; C07D307/52
摘要：
The invention provides derivatives of DEA which have increased potency and hydrolysis resistance as compared to DEA, and compositions thereof, as well as methods of using these derivatives to promote neurogenesis, neurite growth and/or length, and/or promote synaptogenesis.
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