发明授权
- 专利标题： Lipids and compositions for intracellular delivery of biologically active compounds
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申请号： US14178538申请日： 2014-02-12
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公开(公告)号： US09433681B2公开(公告)日： 2016-09-06
- 发明人: Rainer Constien , Anke Geick , Philipp Hadwiger , Torsten Haneke , Ludger Markus Ickenstein , Carla Alexandra Hernandez Prata , Andrea Schuster , Timo Weide
- 申请人： AXOLABS GMBH
- 申请人地址： DE Kulmbach
- 专利权人： AXOLABS GMBH
- 当前专利权人： AXOLABS GMBH
- 当前专利权人地址： DE Kulmbach
- 代理机构： Medler Ferro Woodhouse & Mills PLLC
- 优先权： EP11166353 20110517
- 主分类号： C07C211/22
- IPC分类号： C07C211/22 ; C07D295/30 ; C07D241/04 ; A61K31/713 ; A61K31/7088 ; C07C211/11 ; C07C211/13 ; A61K47/18 ; A61K31/575 ; A61K31/70 ; B82Y5/00 ; C07C217/42 ; C07C211/14 ; C07C217/08 ; C07C217/28 ; A61K9/127 ; A61K9/14 ; A61K38/02 ; A61K47/22 ; A61K39/00
摘要：
The present invention provides novel amino-lipids, compositions comprising such amino-lipids and methods of producing them. In addition, lipid nanoparticles comprising the novel amino-lipids and a biologically active compound are provided, as well as methods of production and their use for intracellular drug delivery.
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