Invention Grant
- Patent Title: PDE9 inhibitors with imidazo triazinone backbone
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Application No.: US14374278Application Date: 2013-01-25
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Publication No.: US09434733B2Publication Date: 2016-09-06
- Inventor: Niels Svenstrup , Klaus Bæk Simonsen , Lars Kyhn Rasmussen , Karsten Juhl , Morten Langgård , Kate Wen , Yazhou Wang
- Applicant: H. Lundbeck A/S
- Applicant Address: DK Valby
- Assignee: H. LUNDBECK A/S
- Current Assignee: H. LUNDBECK A/S
- Current Assignee Address: DK Valby
- Agency: DT Ward, PC
- Agent Donna T. Ward; Heng Zhu
- Priority: WOPCT/CN12/70718 20120126; WOPCT/CN12/80208 20120816
- International Application: PCT/EP2013/051451 WO 20130125
- International Announcement: WO2013/110768 WO 20130801
- Main IPC: C07D487/04
- IPC: C07D487/04

Abstract:
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
Public/Granted literature
- US20150045348A1 PDE9 inhibitors with imidazo triazinone backbone Public/Granted day:2015-02-12
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