发明授权
- 专利标题: Polycyclic compound
- 专利标题(中): 多环化合物
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申请号: US12671873申请日: 2008-08-28
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公开(公告)号: US09453000B2公开(公告)日: 2016-09-27
- 发明人: Teiji Kimura , Noritaka Kitazawa , Toshihiko Kaneko , Nobuaki Sato , Koki Kawano , Koichi Ito , Mamoru Takaishi , Takeo Sasaki , Yu Yoshida , Toshiyuki Uemura , Takashi Doko , Daisuke Shinmyo , Daiju Hasegawa , Takehiko Miyagawa , Hiroaki Hagiwara
- 申请人: Teiji Kimura , Noritaka Kitazawa , Toshihiko Kaneko , Nobuaki Sato , Koki Kawano , Koichi Ito , Mamoru Takaishi , Takeo Sasaki , Yu Yoshida , Toshiyuki Uemura , Takashi Doko , Daisuke Shinmyo , Daiju Hasegawa , Takehiko Miyagawa , Hiroaki Hagiwara
- 申请人地址: JP Tokyo
- 专利权人: EISAI R&D MANAGEMENT CO., LTD.
- 当前专利权人: EISAI R&D MANAGEMENT CO., LTD.
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP2007-225045 20070831; JP2008-020009 20080131; JP2008-123057 20080509
- 国际申请: PCT/JP2008/065365 WO 20080828
- 国际公布: WO2009/028588 WO 20090305
- 主分类号: C07D471/04
- IPC分类号: C07D471/04 ; A61K31/437 ; C07D487/04 ; C07D498/04 ; C07D403/10 ; A61P25/28 ; C07D403/04
摘要:
Disclosed is a compound represented by the formula (I): or a pharmacologically acceptable salt thereof, which is effective as a therapeutic or prophylactic agent for a disease induced by Aβ, wherein Ar1 represents an imidazolyl group which may be substituted with a C1-6 alkyl group, or the like; Ar2 represents a phenyl group which may be substituted with a C1-6 alkoxy group, or the like; X1 represents a double bond, or the like; and Het represents a triazolyl group or the like which may be substituted with a C1-6 alkyl group or the like, or the like.
公开/授权文献
- US20110009619A1 POLYCYCLIC COMPOUND 公开/授权日:2011-01-13
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