Invention Grant
- Patent Title: Dual receptor antagonistic antigen-binding proteins and uses thereof
- Patent Title (中): 双重受体拮抗抗原结合蛋白及其用途
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Application No.: US14407421Application Date: 2013-06-11
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Publication No.: US09453080B2Publication Date: 2016-09-27
- Inventor: Huiquan Han , Xiaolan Zhou , Qing Chen , Mei-Mei Tsai
- Applicant: Amgen Inc.
- Applicant Address: US CA Thousand Oaks
- Assignee: AMGEN INC.
- Current Assignee: AMGEN INC.
- Current Assignee Address: US CA Thousand Oaks
- Agency: Fenwick & West LLP
- International Application: PCT/US2013/045245 WO 20130611
- International Announcement: WO2013/188448 WO 20131219
- Main IPC: C07K16/28
- IPC: C07K16/28 ; C12N15/13 ; C12P21/08 ; A61K39/395 ; C07K16/46 ; A61K39/00
Abstract:
This disclosure relates to antagonistic dual receptor antigen-binding proteins, e.g. antibodies and methods of using the dual receptor antibodies for treatment of pathological diseases. The dual receptor antibodies may comprise an antibody to ActRII receptors and may be used to treat pathological condition. The pathological conditions can comprise muscle wasting diseases or any disease that requires stimulation of muscle growth.
Public/Granted literature
- US20150152194A1 Dual Receptor Antagonistic Antigen-Binding Proteins and Uses Thereof Public/Granted day:2015-06-04
Information query
