Invention Grant
- Patent Title: Solid dispersions of a ERB2 (HER2) inhibitor
- Patent Title (中): ERB2（HER2）抑制剂的固体分散体
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Application No.: US14351840Application Date: 2012-10-12
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Publication No.: US09457093B2Publication Date: 2016-10-04
- Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
- Applicant: Array BioPharma Inc.
- Applicant Address: US CO Boulder
- Assignee: Array BioPharma Inc.
- Current Assignee: Array BioPharma Inc.
- Current Assignee Address: US CO Boulder
- Agency: Viksnins Harris & Padys PLLP
- Agent Corey M. Williams
- International Application: PCT/US2012/060044 WO 20121012
- International Announcement: WO2013/056108 WO 20130418
- Main IPC: A61K47/38
- IPC: A61K47/38 ; A61K31/517 ; A61K47/32 ; A61K9/10 ; A61K9/20 ; A61K9/16
Abstract:
A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
Public/Granted literature
- US20140296267A1 SOLID DISPERSIONS OF A ERB2 (HER2) INHIBITOR Public/Granted day:2014-10-02
Information query
IPC分类:
