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公开(公告)号:US20140296267A1
公开(公告)日:2014-10-02
申请号:US14351840
申请日:2012-10-12
Applicant: Array BioPharma Inc.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
IPC: A61K47/38 , A61K9/10 , A61K47/32 , A61K31/517
CPC classification number: A61K31/517 , A61K9/0053 , A61K9/10 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K47/32 , A61K47/38
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
Abstract translation: N 4 - (4 - ([1,2,4]三唑并[1,5-a]吡啶-7-基氧基)-3-甲基苯基)-N6-(4,4-二甲基-4,5- 二氢恶唑-2-基)喹唑啉-4,6-二胺及其制备方法。 此外,包含N4-(4 - ([1,2,4]三唑并[1,5-α]吡啶-7-基氧基)-3-甲基苯基)-N6-(4,4- 二甲基-4,5-二氢恶唑-2-基)喹唑啉-4,6-二胺及其用途。
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公开(公告)号:US20170136022A1
公开(公告)日:2017-05-18
申请号:US15275163
申请日:2016-09-23
Applicant: Array BioPharma Inc.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
IPC: A61K31/517 , A61K9/00 , A61K9/16 , A61K9/20
CPC classification number: A61K31/517 , A61K9/0053 , A61K9/10 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K47/32 , A61K47/38
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
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公开(公告)号:US09457093B2
公开(公告)日:2016-10-04
申请号:US14351840
申请日:2012-10-12
Applicant: Array BioPharma Inc.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
CPC classification number: A61K31/517 , A61K9/0053 , A61K9/10 , A61K9/1635 , A61K9/1652 , A61K9/2009 , A61K9/2027 , A61K9/2054 , A61K9/2077 , A61K47/32 , A61K47/38
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-α]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
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公开(公告)号:US20230097309A1
公开(公告)日:2023-03-30
申请号:US17895951
申请日:2022-08-25
Applicant: ARRAY BIOPHARMA INC.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
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公开(公告)号:US20210220361A1
公开(公告)日:2021-07-22
申请号:US17133094
申请日:2020-12-23
Applicant: ARRAY BIOPHARMA INC.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
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公开(公告)号:US20190275043A1
公开(公告)日:2019-09-12
申请号:US16353951
申请日:2019-03-14
Applicant: Array BioPharma Inc.
Inventor: David Shank Fry , Christopher M. Lindemann , Michael Preigh , Corey Jay Bloom , Christopher Donovan Craig , Devon Brevard Dubose , Jeff Gautschi , Dan Smithey
Abstract: A solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and processes for preparing the solid dispersion are provided herein. Also, a pharmaceutical composition comprising a solid dispersion of N4-(4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-methylphenyl)-N6-(4,4-dimethyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine and uses thereof are provided herein.
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