Invention Grant
- Patent Title: Isoquinolines as potassium ion channel inhibitors
- Patent Title (中): 异喹啉作为钾离子通道抑制剂
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Application No.: US14771902Application Date: 2014-03-10
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Publication No.: US09458133B2Publication Date: 2016-10-04
- Inventor: Heather Finlay , Ashok Kumar Adisechan , Naveen Kumar Dhondi , Prashantha Gunaga , John Lloyd , Srinivasu Pothukanuri
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Mary K. VanAtten
- International Application: PCT/US2014/022264 WO 20140310
- International Announcement: WO2014/143609 WO 20140918
- Main IPC: C07D217/12
- IPC: C07D217/12 ; C07D401/04 ; C07D405/04 ; A61K31/4709 ; C07D401/12 ; C07D401/14 ; C07D405/14 ; C07D405/12 ; A61K31/4725 ; A61K31/497 ; A61K31/5377 ; C07D417/14
Abstract:
A compound of formula (I) (I) wherein A, R1, R1a, R3 and R24 are described herein. The compounds are useful as inhibitors of potassium channel function and in the treatment and prevention of arrhythmia, IKur-associated disorders, and other disorders mediated by ion channel function.
Public/Granted literature
- US20160016933A1 ISOQUINOLINES AS POTASSIUM ION CHANNEL INHIBITORS Public/Granted day:2016-01-21
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