Invention Grant
- Patent Title: Pyrrolidine derivatives and their use as complement pathway modulators
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Application No.: US14409878Application Date: 2013-06-27
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Publication No.: US09464081B2Publication Date: 2016-10-11
- Inventor: Stefanie Flohr , Ulrich Hommel , Edwige Liliane Jeanne Lorthiois , Jeurgen Klaus Maibaum , Nils Ostermann , Jean Quancard , Stefan Andreas Randl , Olivier Rogel , Anna Vulpetti
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent John B. Alexander
- International Application: PCT/IB2013/055293 WO 20130627
- International Announcement: WO2014/002052 WO 20140103
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D403/14 ; C07D403/06 ; C07D403/12
Abstract:
The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as a factor D inhibitor for the treatment of ophthalmic diseases. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
Public/Granted literature
- US20150322060A1 PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS Public/Granted day:2015-11-12
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