发明授权
- 专利标题: Multigene prognostic assay for lung cancer
- 专利标题(中): 肺癌多基因预后测定
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申请号: US13539278申请日: 2012-06-29
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公开(公告)号: US09476098B2公开(公告)日: 2016-10-25
- 发明人: Michael J. Mann , David M. Jablons , Johannes Kratz , David M. Berryman
- 申请人: Michael J. Mann , David M. Jablons , Johannes Kratz , David M. Berryman
- 申请人地址: US CA Oakland US CA Los Altos
- 专利权人: The Regents of the University of California,Encore Clinical, Inc.
- 当前专利权人: The Regents of the University of California,Encore Clinical, Inc.
- 当前专利权人地址: US CA Oakland US CA Los Altos
- 代理机构: Morrison & Foerster LLP
- 主分类号: C40B30/04
- IPC分类号: C40B30/04 ; C12Q1/68 ; G01N33/574
摘要:
The present invention provides methods for providing a prognosis for lung cancer using a panel of eleven molecular markers that includes BAG1, BRCA1, CDC6, CDK2AP1, ERBB3, FUT3, IL11, LCK, RND3, SH3BGR, and WNT3A, which are differentially expressed in lung cancer. The eleven markers are related to patient prognosis to 5-year overall survival outcomes, and are particularly useful in providing a prognosis for non-squamous NSCLC.
公开/授权文献
- US20130059747A1 MULTIGENE PROGNOSTIC ASSAY FOR LUNG CANCER 公开/授权日:2013-03-07
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