Invention Grant
- Patent Title: Pladienolide pyridine compounds and methods of use
- Patent Title (中): 吡啶衍生物吡啶化合物及其使用方法
-
Application No.: US14710687Application Date: 2015-05-13
-
Publication No.: US09481669B2Publication Date: 2016-11-01
- Inventor: Gregg F. Keaney , John Wang , Baudouin Gerard , Kenzo Arai , Xiang Liu , Guo Zhu Zheng , Kazunobu Kira , Parcharee Tivitmahaisoon , Sudeep Prajapati , Nicholas C. Gearhart , Yoshihiko Kotake , Satoshi Nagao , Regina Mikie Kanada Sonobe , Masayuki Miyano , Norio Murai , Silvia Buonamici , Lihua Yu , Eunice Sun Park , Betty Chan , Peter G. Smith , Michael P. Thomas , Ermira Pazolli , Kian Huat Lim
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Main IPC: C07D405/06
- IPC: C07D405/06 ; C07D405/14 ; A61K31/496
Abstract:
The present invention provides novel pladienolide pyridine compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancer, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful.
Public/Granted literature
- US20150329528A1 Pladienolide Pyridine Compounds and Methods of Use Public/Granted day:2015-11-19
Information query
