Invention Grant
- Patent Title: Cyclopropanamine compound and use thereof
- Patent Title (中): 环丙胺化合物及其用途
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Application No.: US14682695Application Date: 2015-04-09
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Publication No.: US09487511B2Publication Date: 2016-11-08
- Inventor: Shigemitsu Matsumoto , Yasushi Hattori , Masashi Toyofuku , Shinji Morimoto , Masaki Daini , Takuto Kojima , Tomohiro Kaku , Mitsuhiro Ito
- Applicant: Takeda Pharmaceutical Company Limited
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2014-082057 20140411
- Main IPC: C07D333/40
- IPC: C07D333/40 ; C07D333/38 ; C07D407/12 ; C07D409/12 ; C07D417/14 ; C07D417/12 ; C07D307/79 ; C07D213/82 ; C07D413/14 ; C07D231/14 ; C07D285/08 ; C07D285/135

Abstract:
The present invention provides a compound having a lysine-specific demethylase-1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, developmental disorders, particularly diseases having intellectual disability (e.g., autistic spectrum disorders, Rett syndrome, Down's syndrome, Kabuki syndrome, fragile X syndrome, Kleefstra syndrome, neurofibromatosis type 1, Noonan syndrome, tuberous sclerosis), neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, spinocerebellar degeneration (e.g., dentatorubural pallidoluysian atrophy) and Huntington's disease), epilepsy (e.g., Dravet syndrome) or drug dependence, and the like. A compound represented by the formula wherein each symbol is as defined in the present specification, or a salt thereof.
Public/Granted literature
- US20150291577A1 CYCLOPROPANAMINE COMPOUND AND USE THEREOF Public/Granted day:2015-10-15
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