Methods and apparatus for detecting and mitigating interface conditions at a multi-radio device. In one embodiment, a multi-radio device monitors and detects an in-device coexistence (IDC) interference condition which is, for example, caused by concurrent operation of radios. In response, the device notifies a network entity (e.g., a Long Term Evolution (LTE) eNodeB) of the detected IDC condition. Upon receiving the notification of the IDC condition, the network entity may implement or invoke a mitigation scheme in order to reduce the amount of IDC experienced at the client device.