Invention Grant
- Patent Title: PDE9 inhibitors with imidazo triazinone backbone
- Patent Title (中): PDE9抑制剂与咪唑并三酮骨架
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Application No.: US15089819Application Date: 2016-04-04
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Publication No.: US09533992B2Publication Date: 2017-01-03
- Inventor: Niels Svenstrup , Klaus Bæk Simonsen , Lars Kyhn Rasmussen , Karsten Juhl , Morten Langgård , Kate Wen , Yazhou Wang
- Applicant: H. Lundbeck A/S
- Agency: DT Ward, PC
- Agent Donna T. Ward; Heng Zhu
- Priority: WOPCT/CN2012/070718 20120126; WOPCT/CN2012/080208 20120816
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53

Abstract:
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a compound of formula (I) for use in a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I).
Public/Granted literature
- US20160213674A1 PDE9 Inhibitors with Imidazo Triazinone Backbone Public/Granted day:2016-07-28
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