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US09556269B2 Methods for enhancing pathogen clearance by blocking its interaction with paired immunoglobulin-like type 2 receptor (PILR)α 有权
通过阻断其与配对的免疫球蛋白样2型受体(PILR)α的相互作用来增强病原体清除率的方法

  • Patent Title: Methods for enhancing pathogen clearance by blocking its interaction with paired immunoglobulin-like type 2 receptor (PILR)α
  • Patent Title (中): 通过阻断其与配对的免疫球蛋白样2型受体(PILR)α的相互作用来增强病原体清除率的方法
  • Application No.: US14598870
    Application Date: 2015-01-16
  • Publication No.: US09556269B2
    Publication Date: 2017-01-31
  • Inventor: Ali ZarrinYonglian Sun
  • Applicant: Genentech, Inc.
  • Applicant Address: US CA South San Francisco
  • Assignee: Genentech, Inc.
  • Current Assignee: Genentech, Inc.
  • Current Assignee Address: US CA South San Francisco
  • Agency: Clark & Elbing LLP
  • Agent Karen L. Elbing
  • Main IPC: C07K16/28
  • IPC: C07K16/28 G01N33/566 A61K39/395
Methods for enhancing pathogen clearance by blocking its interaction with paired immunoglobulin-like type 2 receptor (PILR)α
Abstract:
Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
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