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公开(公告)号：US12240910B2
公开(公告)日：2025-03-04
申请号：US17864074
申请日：2022-07-13
Applicant: GENENTECH, INC.
Inventor： Gautham Gampa , Iraj Hosseini , Mahrukh Huseni , James Thomas Koerber , Jian Mehr-Dean Payandeh , Sascha Rutz , Yonglian Sun , Cecilia P. C. Chiu , Teresita Arenzana Delfino
IPC: C07K16/28 , A61K39/00 , A61K39/395 , A61K45/06 , A61P35/00
Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
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公开(公告)号：US20230090177A1
公开(公告)日：2023-03-23
申请号：US17994638
申请日：2022-11-28
Applicant: GENENTECH, INC.
Inventor： James Thomas Koerber , Yonglian Sun
IPC: G01N33/531 , G01N33/566 , C07K16/18 , C07K16/10
Abstract: The present disclosure relates to improved methods and compositions for making extracellular vesicles (EVs). The present disclosure also relates to novel EV-based ELISA assays and kits for performing such assays, as well as methods of producing antibodies to particular antigens using EVs comprising membrane-bound antigen.
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3.发明授权Methods for enhancing pathogen clearance by blocking its interaction with paired immunoglobulin-like type 2 receptor (PILR)α 有权通过阻断其与配对的免疫球蛋白样2型受体（PILR）α的相互作用来增强病原体清除率的方法公开(公告)号：US09556269B2
公开(公告)日：2017-01-31
申请号：US14598870
申请日：2015-01-16
Applicant: Genentech, Inc.
Inventor： Ali Zarrin , Yonglian Sun
IPC: C07K16/28 , G01N33/566 , A61K39/395
CPC classification number: C07K16/2803 , A61K39/3955 , C07K16/28 , C07K2317/76 , G01N33/566
Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
Abstract translation: 本文描述的是新的受体 - 配体相互作用和可以修饰和/或阻断相互作用的试剂。 公开了用于调节与其与新受体的相互作用相关的配体活性的方法，用途，试剂和试剂盒。 还公开了试剂治疗炎症相关疾病的治疗用途。
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公开(公告)号：US20230049152A1
公开(公告)日：2023-02-16
申请号：US17864074
申请日：2022-07-13
Applicant: GENENTECH, INC.
Inventor： Gautham Gampa , Iraj Hosseini , Mahrukh Huseni , James T. Koerber , Jian Mehr-Dean Payandeh , Sascha Rutz , Yonglian Sun , Cecilia P. C. Chiu , Teresita A. Delfino
IPC: C07K16/28 , A61K39/395 , A61P35/00 , A61K45/06
Abstract: The present disclosure provides anti-CCR8 antibodies, and compositions and methods of their preparation and use.
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公开(公告)号：US20210301032A1
公开(公告)日：2021-09-30
申请号：US16950418
申请日：2020-11-17
Applicant: Genentech, Inc.
Inventor： Cecilia P.C. Chiu , Hilda Y. Hernandez-Barry , David B. Iaea , Moulay Hicham Alaoui-Ismaili , James T. Koerber , Wei Yu Lin , Kelly Loyet , Yonglian Sun , Benjamin T. Walters , Jawahar Sudhamsu
Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US20250122280A1
公开(公告)日：2025-04-17
申请号：US18927265
申请日：2024-10-25
Applicant: Genentech, Inc.
Inventor： Nicholas John Agard , Thomas Harden Pillow , Josefa Dela Cruz Chuh , Mary Ann T. Go , Katherine R. Kozak , Zhonghua Lin , Dhaya Seshasayee , Shang-Fan Yu , James Thomas Koerber , Yonglian Sun
Abstract: The invention provides anti-Ly6E antibodies and immunoconjugates, and methods of using the same.
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公开(公告)号：US12037412B2
公开(公告)日：2024-07-16
申请号：US16950418
申请日：2020-11-17
Applicant: Genentech, Inc.
Inventor： Cecilia P. C. Chiu , Hilda Y. Hernandez-Barry , David B. Iaea , Moulay Hicham Alaoui-Ismaili , James T. Koerber , Wei Yu Lin , Kelly Loyet , Yonglian Sun , Benjamin T. Walters , Jawahar Sudhamsu
CPC classification number: C07K16/40 , A61K47/6871 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-kallikrein-related peptidase 5 (KLK5) antibodies and methods of using the same.
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公开(公告)号：US20200040103A1
公开(公告)日：2020-02-06
申请号：US16352619
申请日：2019-03-13
Applicant: Genentech, Inc.
Inventor： Cecilia P. C. Chiu , Hilda Y. Hernandez-Barry , David B. Iaea , Moulay Hicham Alaoui-Ismaili , James T. Koerber , Wei Yu Lin , Kelly Loyet , Yonglian Sun , Benjamin T. Walters , Jawahar Sudhamsu
Abstract: The invention provides anti-KLK5 antibodies and methods of using the same.
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公开(公告)号：US10160807B2
公开(公告)日：2018-12-25
申请号：US15397399
申请日：2017-01-03
Applicant: Genentech, Inc.
Inventor： Ali Zarrin , Yonglian Sun
IPC: C07K16/28 , G01N33/566 , A61K39/395
Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
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公开(公告)号：US20130344080A1
公开(公告)日：2013-12-26
申请号：US13921557
申请日：2013-06-19
Applicant: GENENTECH, INC.
Inventor： Ali Zarrin , Yonglian Sun
IPC: A61K39/395
CPC classification number: C07K16/2803 , A61K39/3955 , C07K16/28 , C07K2317/76 , G01N33/566
Abstract: Described herein is a novel receptor-ligand interaction and agents that may modify and/or block the interaction. Methods, uses, reagents and kits for the modulation of ligand activities related to its interaction with the novel receptor are disclosed. Also disclosed are therapeutic uses of reagents in treating inflammation-related disorders.
Abstract translation: 本文描述的是新的受体 - 配体相互作用和可以修饰和/或阻断相互作用的试剂。 公开了用于调节与其与新受体的相互作用相关的配体活性的方法，用途，试剂和试剂盒。 还公开了试剂治疗炎症相关疾病的治疗用途。
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