Invention Grant
- Patent Title: Nanopore-based sequencing with varying voltage stimulus
- Patent Title (中): 具有不同电压刺激的基于纳米孔的测序
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Application No.: US14577511Application Date: 2014-12-19
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Publication No.: US09557294B2Publication Date: 2017-01-31
- Inventor: Roger J. A. Chen , Hui Tian , Bill Maney
- Applicant: Genia Technologies, Inc.
- Applicant Address: US CA Santa Clara
- Assignee: Genia Technologies, Inc.
- Current Assignee: Genia Technologies, Inc.
- Current Assignee Address: US CA Santa Clara
- Agency: Van Pelt, Yi & James LLP
- Main IPC: G01N27/447
- IPC: G01N27/447 ; B01L3/00 ; C12Q1/68 ; G01N33/487
Abstract:
A method of analyzing a molecule in a nanopore is disclosed. A voltage is applied across a nanopore that is inserted in a membrane by coupling the nanopore to a voltage source. The nanopore is decoupled from the voltage source. After the decoupling, a rate of decay of the voltage across the nanopore is determined. A molecule in the nanopore is distinguished from other possible molecules based on the determined rate of decay of the voltage across the nanopore.
Public/Granted literature
- US20160178577A1 NANOPORE-BASED SEQUENCING WITH VARYING VOLTAGE STIMULUS Public/Granted day:2016-06-23
Information query
