发明授权
- 专利标题: Method for screening drugs for suppressing inflammasome activity
- 专利标题(中): 用于筛选药物以抑制炎症性活性的方法
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申请号: US13885950申请日: 2011-11-17
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公开(公告)号: US09557321B2公开(公告)日: 2017-01-31
- 发明人: Tatsutoshi Nakahata , Megumu Saito , Takayuki Tanaka , Shinya Yamanaka
- 申请人: Tatsutoshi Nakahata , Megumu Saito , Takayuki Tanaka , Shinya Yamanaka
- 申请人地址: JP Kyoto-shi, Kyoto
- 专利权人: KYOTO UNIVERSITY
- 当前专利权人: KYOTO UNIVERSITY
- 当前专利权人地址: JP Kyoto-shi, Kyoto
- 代理机构: Knobbe, Martens, Olson & Bear LLP
- 国际申请: PCT/JP2011/077265 WO 20111117
- 国际公布: WO2012/067265 WO 20120524
- 主分类号: C12N5/00
- IPC分类号: C12N5/00 ; G01N33/50 ; C12N5/074 ; G01N33/68
摘要:
The present invention provides a method for screening drugs for suppressing inflammasome activity, using macrophages derived from induced pluripotent stem cells (iPS cells) having mutant NLRP3 gene.
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