A system and a method for luminance correction that can remove luminance spots of a display device. The system includes a display device, an image detection unit, and a luminance correction device. The display device includes a plurality of sub-pixels including first sub-pixels and corresponding second sub-pixels. The image detection unit is configured to measure respective luminance values of the first sub-pixels. The luminance correction device is configured to supply test data so that only the first sub-pixels emit light, and to calculate correction values corresponding to the plurality of sub-pixels based on difference values between the respective luminance values measured by the image detection unit and one or more target luminance values.