Invention Grant
- Patent Title: Methods of treating autophagy-associated disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits
- Patent Title (中): 治疗自噬相关疾病和相关药物组合物，诊断，筛选技术和试剂盒的方法
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Application No.: US14116581Application Date: 2012-05-10
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Publication No.: US09572820B2Publication Date: 2017-02-21
- Inventor: Vojo Deretic , Eliseo Castillo , Steven Bradfute , Larry A. Sklar
- Applicant: Vojo Deretic , Eliseo Castillo , Steven Bradfute , Larry A. Sklar
- Applicant Address: US NM Albuquerque
- Assignee: STC.UNM
- Current Assignee: STC.UNM
- Current Assignee Address: US NM Albuquerque
- Agent Henry D. Coleman; R. Neil Sudol
- International Application: PCT/US2012/037300 WO 20120510
- International Announcement: WO2012/154944 WO 20121115
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/12 ; A61K31/65 ; C07K16/18 ; G01N33/68 ; A61K31/436 ; A61K31/4365 ; A61K31/4535 ; A61K31/472 ; A61K31/473 ; A61K31/517 ; A61K31/522 ; A61K31/54 ; A61K31/546 ; A61K31/5685 ; A61K31/585 ; G01N33/569
Abstract:
The invention provides methods of treating autophagy mediated diseases and disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention provides a method of determining whether a subject suffers from, or is at risk of developing, and autophagy mediated disease state and/or condition by evaluating LC3 levels.
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