A rear slider window assembly for a vehicle includes a frame portion having an upper rail and a lower rail, a fixed window panel that is fixed relative to the frame portion, and a movable window panel that is movable along the upper and lower rails. The movable window panel has a first electrical element established at a surface thereof. The first electrical element is in electrical connection with a vehicle power source via a flexible cable having one end electrically connected to the first electrical element at the movable window panel and another end electrically connected to a second electrical connector at the fixed window panel. The flexible cable flexes in response to movement of the movable window panel relative to the fixed window panel. A wire guide is disposed at the fixed window panel and the flexible cable is routed along the wire guide.