Embodiments of the invention provide medication dispensing carts and methods. The medication dispensing carts may include a base having wheels that allow the carts to be transported within a facility, a computing device configured to receive input from a user, a display device communicatively coupled with the computing device for displaying information to the user, a post that couples the display device with the base, and a plurality of cassettes that have one or more bins within which medical supplies are stored. The plurality of cassettes may be coupled with the post and the post may include a plurality of communication ports that communicatively couple one or more of the cassettes with the computing device to perform or provide various functions.