Invention Grant
- Patent Title: Antibodies with modified isoelectric points
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Application No.: US14165487Application Date: 2014-01-27
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Publication No.: US09605061B2Publication Date: 2017-03-28
- Inventor: Gregory A. Lazar , Bassil I. Dahiyat , Matthew J. Bernett
- Applicant: XENCOR, INC.
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Robin M. Silva; Louis T. Nguyen
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C07K16/22 ; C07H21/00 ; C07K14/00
Abstract:
The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e.g. increased serum half-life in vivo.
Public/Granted literature
- US20140249297A1 ANTIBODIES WITH MODIFIED ISOELECTRIC POINTS Public/Granted day:2014-09-04
Information query
